Clarity

Clarity产品组合中的每款产品都经过专门设计，旨在高效纯化或表征生物研究、治疗开发和生化生产中使用的合成寡核苷酸。用于寡核苷酸分析的 Clarity HPLC 色谱柱的特点如下：

从目标寡核苷酸中轻松分离 N-1 失败序列，纯度大于 90 %
脱三苯甲基纯化 DNA、RNA、硫醇、改性/标记寡核苷酸
制备规格和粒径适用于大于 5 μmol 的载样
纯化长度达 60 mer 的寡核苷酸
适用于反相 HPLC 质量控制 (QC) 的出色色谱柱

系列概述
产品规格
产品文件
产品应用
使用维护
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LC-MS 分析

Clarity Oligo-XT

从分析级到制备级色谱的推荐方案
pH稳定范围1-12
兼容100%水相流动相
核-壳颗粒技术提供更快的分离速度、更高的分辨率和灵敏度
可轻松将分析型LC-MS方法放大至制备规模用于分离/纯化
1.7µm颗粒性能优于现有亚2µm方法

Clarity Oligo-MS

适用于需要不同选择性的分析级色谱分离
pH稳定范围1.5-8.5
核-壳颗粒技术提供更快的分离速度、更高的分辨率和灵敏度
可轻松将定量LC-MS方法转移至大多配备2.6µm颗粒的系统
1.7µm颗粒性能优于现有亚2µm方法

Clarity Oligo-RP

适用于需要不同选择性的分析级到制备级色谱分离
pH稳定范围1.0-12
硅胶杂化技术形成杂化颗粒，提高耐用性
可轻松将分析型LC-MS方法放大至制备规模用于分离/纯化

材料特性

Clarity Products Porous	Particle Support	Bonded Phase	Particle Shape/Size (μm)	Pore Size(Å)	Surface Area (m²/g)
Clarity Oligo-XT LC Columnsaph="1">Core-shell	C18	1.7, 2.6, 5	100	200
Clarity Oligo-MS LC Columns	Core-shell	C18	1.7, 2.6, 5	100	200
Clarity Oligo-RP LC Columns	TWIN (silica, organic composite) C18 3, 5, 10 110 375	C18	3, 5, 10	110	375

Clarity BioSolutions 产品选择

纯化

	Clarity QSP™	Clarity Oligo-RP™ LC Columns Clarity Oligo-XT LC Columns	Clarity RP-Desalting™
Primary Use	High-throughput, trityl-on RPC purification	RP-HPLC purification of failure sequences from target sequences	Quick removal or salt & excess reagent
Purities	>90%	>90%	~70%
Recoveries	~90%	~70%	~70%
Synthesis Scale Load	Up to 50 µmol	Up to 50 µmol	Up to 1 µmol
Oligo Types	DNA, RNA/RNAi, Thioates, Dye-labled, Modified

表征/分析

	Clarity Oligo-RP™ LC Columns	Clarity Oligo-MS™ LC Columns Clarity Oligo-XT LC Columns	Clarity OTX™ LC Columns
Primary Use	RP-LC-MS analysis with optimized selectivity and sensitivity	Rapid, high efficiency RP-LC-MS analysis for QC and characterization	Extraction of oligo therapeutics from biological samples for LC-MS bioanalysis
Oligo Length	≤ 60 mer	≤ 60 mer	≤ 40 mer
Recommended Mobile Phase	TEA / HFIP	TEA/HFIP/MeOH	N/A

产品记录： 共找到 44 条记录

产品货号	产品名称	产品描述
00F-4445-N0	Clarity® 10 µm Oligo-RP	LC Column 150 x 10 mm
00B-4746-E0	Clarity® 2.6 µm Oligo-XT 100 Å	LC Column 50 x 4.6 mm
00D-4479-E0	Clarity® 2.6 µm Oligo-MS 100A	LC Column 100 x 4.6 mm
00B-4442-N0	Clarity® 5 µm Oligo-RP	LC Column 50 x 10 mm
00G-4445-P0-AX	Clarity® 10 µm Oligo-RP	LC Column 250 x 21.2 mm, AXIA™ Packed
00F-4745-U0-AX	Clarity® 5 µm Oligo-XT 100Å	LC Column 150 x 30.0 mm, AXIA™-Packed
00B-4747-AN	Clarity® 1.7 µm Oligo-XT 100 Å	LC Column 50 x 2.1 mm
00B-4441-B0	Clarity® 3 µm Oligo-RP	LC Column 50 x 2 mm
00D-4480-AN	Clarity® 1.7 µm Oligo-MS 100A	LC Column 100 x 2.1 mm
00B-4746-AN	Clarity® 2.6 µm Oligo-XT 100 Å	LC Column 50 x 2.1 mm
00D-4442-P0-AX	Clarity® 5 µm Oligo-RP	LC Column 100 x 21.2 mm, AXIA™ Packed
00B-4441-E0	Clarity® 3 µm Oligo-RP	LC Column 50 x 4.6 mm
00D-4441-B0	Clarity® 3 µm Oligo-RP	LC Column 100 x 2 mm
00G-4445-N0	Clarity® 10 µm Oligo-RP	LC Column 250 x 10 mm
00G-4445-E0	Clarity® 10 µm Oligo-RP	LC Column 250 x 4.6 mm
00D-4746-E0	Clarity® 2.6 µm Oligo-XT 100 Å	LC Column 100 x 4.6 mm
00F-4441-B0	Clarity® 3 µm Oligo-RP	LC Column 150 x 2 mm
00G-4442-U0-AX	Clarity® 5 µm Oligo-RP	LC Column 250 x 30 mm, AXIA™ Packed
00D-4479-AN	Clarity® 2.6 µm Oligo-MS 100A	LC Column 100 x 2.1 mm
00F-4442-N0	Clarity® 5 µm Oligo-RP	LC Column 150 x 10 mm
00F-4442-E0	Clarity® 5 µm Oligo-RP	LC Column 150 x 4.6 mm
00F-4445-U0-AX	Clarity® 10 µm Oligo-RP	LC Column 150 x 30 mm, AXIA™ Packed
00F-4441-E0	Clarity® 3 µm Oligo-RP	LC Column 150 x 4.6 mm
00B-4745-AN	Clarity® 5 µm Oligo-XT 100 Å	LC Column 50 x 2.1 mm
00G-4442-N0	Clarity® 5 µm Oligo-RP	LC Column 250 x 10 mm
00D-4745-N0	Clarity® 5 µm Oligo-XT 100 Å	LC Column 100 x 10.0 mm
00F-4745-P0-AX	Clarity® 5 µm Oligo-XT 100Å	LC Column 150 x 21.2 mm, AXIA™-Packed
00B-4480-AN	Clarity® 1.7 µm Oligo-MS 100A	LC Column 50 x 2.1 mm
00G-4442-E0	Clarity® 5 µm Oligo-RP	LC Column 250 x 4.6 mm
00B-4441-N0	Clarity® 3 µm Oligo-RP	LC Column 50 x 10 mm
00D-4442-N0	Clarity® 5 µm Oligo-RP	LC Column 100 x 10 mm
00B-4479-AN	Clarity® 2.6 µm Oligo-MS 100A	LC Column 50 x 2.1 mm
00F-4442-P0-AX	Clarity® 5 µm Oligo-RP	LC Column 150 x 21.2 mm, AXIA™ Packed
00F-4442-B0	Clarity® 5 µm Oligo-RP	LC Column 150 x 2 mm
00D-4442-U0-AX	Clarity® 5 µm Oligo-RP	LC Column 100 x 30.0 mm, AXIA™-Packed
00B-4745-N0	Clarity® 5 µm Oligo-XT 100 Å	LC Column 50 x 10.0 mm
00B-4442-E0	Clarity® 5 µm Oligo-RP	LC Column 50 x 4.6 mm
00F-4445-P0-AX	Clarity® 10 µm Oligo-RP	LC Column 150 x 21.2 mm, AXIA™ Packed
00G-4442-P0-AX	Clarity® 5 µm Oligo-RP	LC Column 250 x 21.2 mm, AXIA™ Packed
00A-4441-B0	Clarity® 3 µm Oligo-RP	LC Column 30 x 2 mm
00D-4747-AN	Clarity® 1.7 µm Oligo-XT 100 Å	LC Column 100 x 2.1 mm
00D-4746-AN	Clarity® 2.6 µm Oligo-XT 100 Å	LC Column 100 x 2.1 mm
00F-4745-E0	Clarity® 5 µm Oligo-XT 100 Å	LC Column 150 x 4.6 mm
00D-4441-E0	Clarity® 3 µm Oligo-RP	LC Column 100 x 4.6 mm